Ovarian cancer is the leading cause of death among malignant tumours of the pelvic genital tract.
The anatomical extension and intra-abdominal distribution routes also explain the seriousness of this cancer and its often late diagnosis, which in turn explains its dreadful prognosis.
Risk factors are still poorly understood. The use of oral contraceptives appears to reduce the risk of ovarian cancer.
Any suspected ovarian lesion should undergo a full extension workup prior to surgery, which will also enable the tumor to be staged.
Ultrasound can be used to make a diagnosis, but it alone cannot determine the extent of this tumour, which is intraperitoneal (in the abdominal cavity), or assess lymph node involvement.
MRI allows us to assess this extension, which will be reassessed during the operation, most often performed laparoscopically.
Only limited, low-grade tumors in young women can benefit from a limited surgical procedure, such as removal of the adnexa (tube + ovary) on one side only, to preserve the patient's fertility.
In most cases, the surgical procedure will be complete, combining hysterectomy, removal of the adnexa, omentectomy (removal of the omentum) and complete lymph node dissection (pelvic and lumbo-aortic).
Combining surgery and chemotherapy is essential, and can be done either before or after.
This decision is made on a case-by-case basis at a multidisciplinary consultation meeting between the surgeon and oncologists.